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Home Health - Disease Information Why shouldn't you mix Benadryl and Alcohol?

Why shouldn’t you mix Benadryl and Alcohol?

Why shouldn’t you mix Benadryl and Alcohol?

Benadryl And Alcohol
Benadryl And Alcohol

Mixing Benadryl and Alcohol can be powerful as they both slow down the CNS (central nervous system). Due to which you can feel drowsiness, sedation and cause problems to perform both mental and physical tasks.

Benadryl is a brand of the drug used to treat allergies, hay fever, the common cold or cough. It is an over-the-counter (OTC) medication that is used for allergies.

You can get it without a prescription from a doctor or pharmacist. Benadryl has an antihistamine that blocks the natural histamine that occurs in your body.

Histamine is a chemical that is produced by your immune system. Protect your body from foreign particles. It can make you sneeze, cry or itch, whatever it takes to get the foreign particles out of your body.

Your overreaction can cause restlessness and confusion. To suppress the effects of histamine, you need the antihistamine, i.e. Benadryl.

Benadryl is a water-soluble medicine and is quickly absorbed by the body and reaches its maximum level in one hour. It is processed by the liver and can remain in the body for about 24 hours. It can be lethal if you use more than 300 milligrams a day. The 300 milligrams should also be divided into 25-50 milligram doses.

Benadryl for children

Benadryl should not be used for babies under two years of age. Babies do not produce histamine in large amounts, and it can affect their brain. Children 4 years and older can take Benadryl but in a much lower quantity. The recommended doses for children should not be more than two times in 24 hours.

Uses of Benadryl

  • relieve allergy
  • hay fever
  • the common cold
  • eruption
  • itchiness
  • crying eyes
  • itchy eyes / nose / throat
  • Cough
  • A runny nose

Benadryl is an over-the-counter treatment for allergies and a runny nose. You can buy it without a prescription at any local store. It can make you sleepy and help you sleep better. There are some common side effects of it.

Common side effects of Benadryl

  • Sedation,
  • fatigue,
  • drowsiness,
  • dizziness,
  • disturbed coordination,
  • constipation,
  • dry mouth / nose / throat,
  • Difficulty urinating
  • Stomachache.
  • Blurry vision
  • double vision
  • loss of appetite or
  • nausea

What is alcohol?

Alcohol is a legal but sedative drug that does not contain nutrients for the body. It reduces a person’s ability to think rationally and distorts his judgment. There are some benefits of alcohol, especially red wine. It is also a depressant that slows down the functioning of the central nervous system.

Most people drink alcohol to calm down. It is found in most social gatherings. It has anxiety-reducing properties. The human body has a limit to everything. If you drink more alcohol than your body can handle, you will experience sedative effects.

It can create social and physical complication for you. The amount of alcohol you drink determines the type of effect of personal experience.

Drinking too much alcohol can lead to addiction, liver cirrhosis, or liver failure. An adult person should not drink alcohol more than 75 g at a time.

The lethal amount of alcohol per 60 kg person is 300 g. It can kill the person. It can remain in your body’s system for 24-48 hours. In addition, it can be detected by urine, saliva, or a breath test.

Ethanol alcohol is only alcohol used in beverages. It is produced by fermentation of grains and fruits. It is available in many drinks such as beer, wine for the most powerful distilled spirits such as whiskey.

The side effect of alcohol

  • Losing coordination and control of the body.
  • Inability to feel pain,
  • toxicity where the body vomits the poison
  • worse unconsciousness
  • eat
  • death from a severe toxic overdose
  • Possible respiratory depression
  • Urinary incontinence
  • Lethargy
  • Confusion
  • Slower reflexes
  • Decreased heart rate
  • Blurry vision
  • Increase the damage rate.

Benadryl and alcohol are powerful medications and must be taken with care. In addition to the common side effects, drinking alcohol with Benadryl can cause serious harm.

Risks of mixing Benadryl and alcohol

The danger of mixing Benadryl and alcohol

Benadryl and alcohol are depressants for the central nervous system of the human body. Mixing both can depress the central nervous system too much.

1. Sleep problem

Benadryl approves that sleep aid and alcohol also numb him. When Benadryl is mixed with alcohol instead of sleeping well, it can act as a stimulant. It can make you dizzy and uneasy.

Overdosing on Benadryl and alcohol can cause sedation and drowsiness, which can further impair your coordination and reaction. The mixture can be dangerous and impair daily function. If done daily, it can be life-threatening and interrupt your daily activities.

2. Driving warning

One of the driving rules is “don’t drink and drive”. When Benadryl is added to alcohol, it increases the effects of alcohol over a longer period.

A mixture of Benadryl and alcohol can have a greater impact on your ability to stay alert. You may encounter an accident or injury. So this is another side effect that you can’t handle after drinking the Benadryl and alcohol mixture.

3. Addiction to combination

Both alcohol and Benadryl are easy products to obtain at a normal price. Many alcoholics find the effect of the combination desirable, but it is detrimental to health.

Experts say the combination is quite addictive. Daily use of this mixture may soon become a habit and give you long-term health problems.

4. Cause cardiovascular problems for the elderly

The combination of alcohol and Benadryl can cause much more dangerous for older people. It can affect the motor activity of older people and create a heart attack in many.

It is because the functioning of the heart of the elderly is not as strong compared to young adults. Also, the heart of the elderly is insignificant to handle the high dose of this mixture.

5. Loss of consciousness

For some people, it is easy to lose their mental state or consciousness. For them, the mixture of Benadryl and alcohol can easily make them uncontrollable and unaware of their own state.

This can cause additional problems like disputes, falls or accidents.

6. Dehydration

Benadryl and alcohol are known to dehydrate your body to a great extent. When mixed, they can further increase the dehydration rate.

Dehydration can make you feel weak, make your body shake, and even make your hangover worse.

7. It damages learning and memory

Benadryl can stop the action of a very important brain neurotransmitter called acetylcholine. Acetylcholine is an important brain neurotransmitter that is related to memory and learning. A blockage in its action can significantly affect its operation. On the other hand, alcohol is known to temporarily block your learning and memory process. Therefore, when you combine Benadryl and alcohol together, it can have a noticeable effect on your learning and memory, and in the long run, it may even interrupt it.

8. Interact with other medications

Benadryl can interact with other types of medications and cause a variety of side effects. The same is with alcohol. When both are combined, it can increase side effects and cause a variety of health problems. Therefore, it is always better to avoid taking medications.

Medications that can interact with Benadryl and alcohol are as follows:

  • Antihistamines
  • cough medicine
  • stomach ulcer medication
  • Sedatives
  • Diazepam

9. For women, the mixture is more harmful

Females are more susceptible to the side effects of alcohol. It is because your body contains less water to mix the alcohol. It means that the same amount of alcohol can be more concentrated in the female body than in the male body.

Mixing Benedryl with alcohol can cause a number of dangerous effects. Even when consumed in small doses, the levels can cause adverse side effects.

10. Insanity

Studies suggest that people who take Benadryl and alcohol daily for three years may be at risk for dementia. Not only this alcohol, when mixed with any anticholinergic medication, not only Benadryl, can cause an increased risk of dementia.

However, the research has valid reasons for only very high doses of benadryl and alcohol. Occasional small doses cannot cause such problems.

The tolerability of the combination depends on person to person. Some people may not have a mixing effect, while others develop an immediate effect. The combination can have serious consequences on your health.

For the medium effect, it can include nausea and vomiting. The combination can have serious consequences on your health.

For the medium effect, it can include nausea and vomiting. The life-threatening situation can occur if you drink a mixture of alcohol and Benadryl. It can cause internal bleeding and cardiac arrest.

Patients with asthma or COPD are at high risk of suppression or respiratory failure.


Always avoid drinking alcohol after Benadryl or vice versa. If you have to drink alcohol, wait a few hours until the body wears off the effects of Benadryl.

If you take Benadryl, ask your doctor how long you should wait before drinking a glass of alcohol. Never take a combination of alcohol and Benadryl to avoid side effects or consequences.

Some over-the-counter or prescription medications may contain up to 10% alcohol. Drugs like laxatives and cough syrup have an adequate amount of alcohol.

These drugs can interact with Benadryl and cause harm to you. To avoid any interaction of alcohol and Benadryl, always read the label before using any medication.

Can the combination of Benadryl and alcohol kill him?

Yes, it is strong enough to kill you. Too much of any of them is dangerous. Both are depressants of the central nervous system. The combination produces deep dizziness and drowsiness. The person loses control over the mind and body. When combined, the depressant effect is greatly increased. It can shut down the central nervous system.

What to do if someone had taken the combination of Benadryl and alcohol?

The effect of Benadryl and alcohol differ from person to person. You can treat dry mouth caused by the mixture of Benadryl and alcohol.

Give the patient sugar-free candy or gum, use ice chips or any juice. Avoid giving other drugs to the patient.

If a person is sleepy without any problem, let him sleep. The effect of the combination will be removed by itself. If vomiting or a breathing problem occurs, you should take him to the hospital or see a doctor immediately.

Why shouldn't you mix Benadryl and Alcohol?
Mustafa Rangoonwala
I'm Mustafa Rangoonwala having more than 10 years of working experience in the Health and Wellness Industry. I love to write articles on Ganoderma Lucidum, Health and Wellness, Relationship, SEO, Digital Marketing etc


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